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1

Clonidine produces a conditioned place preference in rats

Karen E. Asin, David Wirtshafter

Journal:

Psychopharmacology

Year:

1985

Language:

english

File:

PDF, 281 KB

english, 1985

2

Differential effects of serotonergic and catecholaminergic drugs on ingestive behavior

Karen E. Asin, John D. Davis, Lisa Bednarz

Journal:

Psychopharmacology

Year:

1992

Language:

english

File:

PDF, 988 KB

english, 1992

3

Dopamine antagonists induce fos-like-immunoreactivity in the substantia nigra and entopeduncular nucleus of the rat

David Wirtshafter, Karen E. Asin

Journal:

Year:

1995

Language:

english

File:

PDF, 1.68 MB

english, 1995

4

Amphetamine induces Fos-like immunoreactivity in the striatum of primates

Karen E. Asin, David Wirtshafter, Arthur Nikkel

Journal:

Year:

1996

Language:

english

File:

PDF, 793 KB

english, 1996

5

MK-801 differentially affects dopamine D1 and D2 receptor agonist-induced behavioral tolerance and desensitization

Karen E. Asin, Lisa Bednarz, Arthur L. Nikkel

Journal:

Year:

1996

Language:

english

File:

PDF, 796 KB

english, 1996

6

Lysine vasopressin attenuation of diethyldithiocarbamate-induced amnesia

Journal:

Pharmacology Biochemistry and Behavior

Year:

1980

Language:

english

File:

PDF, 415 KB

english, 1980

7

Force requirements in lever-pressing and responding after haloperidol

Karen E. Asin, H.C. Fibiger

Journal:

Pharmacology Biochemistry and Behavior

Year:

1984

Language:

english

File:

PDF, 382 KB

english, 1984

8

Haloperidol and nonreinforcement produce different patterns of response slowing in a food reinforced runway task

David Wirtshafter, Karen E. Asin

Journal:

Pharmacology Biochemistry and Behavior

Year:

1985

Language:

english

File:

PDF, 292 KB

english, 1985

9

Evidence against serotonin involvement in the hyperactivity produced by injections of muscimol into the median raphe nucleus

David Wirtshafter, Mark A. Klitenick, Karen E. Asin

Journal:

Pharmacology Biochemistry and Behavior

Year:

1987

Language:

english

File:

PDF, 844 KB

english, 1987

10

Is dopamine involved in the hyperactivity produced by injections of muscimol into the median raphe nucleus?

David Wirtshafter, Mark A. Klitenick, Karen E. Asin

Journal:

Pharmacology Biochemistry and Behavior

Year:

1988

Language:

english

File:

PDF, 630 KB

english, 1988

11

Evidence for dopamine involvement in reinforcement obtained using a latent extinction paradigm

Karen E. Asin, David Wirtshafter

Journal:

Pharmacology Biochemistry and Behavior

Year:

1990

Language:

english

File:

PDF, 358 KB

english, 1990

12

Dissociation of haloperidol-induced “anhedonia” and catalepsy by lesions of the dorsal raphe nucleus

David Wirtshafter, Karen E. Asin

Journal:

Pharmacology Biochemistry and Behavior

Year:

1991

Language:

english

File:

PDF, 354 KB

english, 1991

13

Comparative effects of scopolamine and quinpirole on the striatal fos expression induced by stimulation of D1 dopamine receptors in the rat

David Wirtshafter, Karen E. Asin

Journal:

Year:

2001

Language:

english

File:

PDF, 1.33 MB

english, 2001

14

Compartmentally specific effects of quinpirole on the striatal Fos expression induced by stimulation of D1-dopamine receptors in intact rats

David Wirtshafter, Greg Schardt, Karen E Asin

Journal:

Year:

1997

Language:

english

File:

PDF, 247 KB

english, 1997

15

Unilateral dopamine depletion paradoxically enhances amphetamine-induced Fos expression in basal ganglia output structures

David Wirtshafter, Karen E Asin

Journal:

Year:

1999

Language:

english

File:

PDF, 411 KB

english, 1999

16

Haloperidol induces Fos expression in the globus pallidus and substantia nigra of cynomolgus monkeys

David Wirtshafter, Karen E. Asin

Journal:

Year:

1999

Language:

english

File:

PDF, 557 KB

english, 1999

17

Dopamine agonists and stress produce different patterns of Fos-like immunoreactivity in the lateral habenula

David Wirtshafter, Karen E. Asin, Mark R. Pitzer

Journal:

Year:

1994

Language:

english

File:

PDF, 1.44 MB

english, 1994

18

A-69024: a non-benzazepine antagonist with selectivity for the dopamine D-1 receptor

Daniel J. Kerkman, Martha Ackerman, Linda D. Artman, Robert G. MacKenzie, Marty C. Johnson, Lisa Bednarz, William Montana, Karen E. Asin, Herman Stampfli, John W. Kebabian

Journal:

European Journal of Pharmacology

Year:

1989

Language:

english

File:

PDF, 789 KB

english, 1989

19

A68930: a potent agonist selective for the dopamine D1 receptor

Michael P. DeNinno, Robert Schoenleber, Robert MacKenzie, Donald R. Britton, Karen E. Asin, Clark Briggs, Joel M. Trugman, Martha Ackerman, Linda Artman, Lisa Bednarz, Ramesh Bhatt, Peter Curzon, Edwi

Journal:

European Journal of Pharmacology

Year:

1991

Language:

english

File:

PDF, 1.55 MB

english, 1991

20

Effects of repeated dopamine D1 receptor stimulation on rotation and c-fos expression

Karen E. Asin, David Wirtshafter

Journal:

European Journal of Pharmacology

Year:

1993

Language:

english

File:

PDF, 193 KB

english, 1993

21

Hyperactivity and behavioral seizures in rodents following treatment with the dopamine D1 receptor agonists A-86929 and ABT-431

Kazumi Shiosaki, Karen E Asin, Donald R Britton, William J Giardina, Lisa Bednarz, Laura Mahan, Joe Mikusa, Arthur Nikkel, Carol Wismer

Journal:

European Journal of Pharmacology

Year:

1996

Language:

english

File:

PDF, 177 KB

english, 1996

22

Nucleus accumbens lesions reduce amphetamine hyperthermia but not hyperactivity

David Wirtshafter, Karen E. Asin, Ernest W. Kent

Journal:

European Journal of Pharmacology

Year:

1978

Language:

english

File:

PDF, 312 KB

english, 1978

23

Impaired patterned responding in rats with electrolytic median raphe lesions

Karen E. Asin, David Wirtshafter, Ernest W. Kent

Journal:

Physiology & Behavior

Year:

1979

Language:

english

File:

PDF, 389 KB

english, 1979

24

Simple technique for midline stereotaxic surgery in the rat

David Wirtshafter, Karen Asin, Ernest W. Kent

Journal:

Physiology & Behavior

Year:

1979

Language:

english

File:

PDF, 137 KB

english, 1979

25

Ingestive behaviors of rats with electrolytic median raphe lesions maintained on a food deprivation schedule

Karen E. Asin, David Wirtshafter

Journal:

Physiology & Behavior

Year:

1982

Language:

english

File:

PDF, 453 KB

english, 1982

26

A comment on the practice of expressing food and water intake as a proportion of body weight

David Wirtshafter, Karen E. Asin

Journal:

Physiology & Behavior

Year:

1982

Language:

english

File:

PDF, 250 KB

english, 1982

27

Evidence that electrolytic median raphe lesions increase locomotion but not exploration

David Wirtshafter, Karen E. Asin

Journal:

Physiology & Behavior

Year:

1982

Language:

english

File:

PDF, 786 KB

english, 1982

28

Discrimination learning and reversal following electrolytic lesions of the median raphe nucleus

David Wirtshafter, Karen E. Asin

Journal:

Physiology & Behavior

Year:

1986

Language:

english

File:

PDF, 944 KB

english, 1986

29

An analysis of neuronal elements within the median nucleus of the raphe that mediate lesion-induced increases in locomotor activity

Karen E. Asin, H.C. Fibiger

Journal:

Year:

1983

Language:

english

File:

PDF, 2.52 MB

english, 1983

30

Alterations in drug induced catalepsy and post-decapitation convulsions following brain and spinal cord depletion of norepinephrine by the neurotoxin DSP-4

Karen E. Asin, David Wirtshafter, Hans C. Fibiger

Journal:

Year:

1982

Language:

english

File:

PDF, 283 KB

english, 1982

31

Straight alley acquisition and extinction and open field activity following discrete electrolytic lesions of the mesencephalic raphe nuclei

Karen E. Asin, David Wirtshafter, Ernest W. Kent

Journal:

Behavioral and Neural Biology

Year:

1979

Language:

english

File:

PDF, 2.71 MB

english, 1979

32

The effects of electrolytic median raphe lesions on two measures of latent inhibition

Karen E. Asin, David Wirtshafter, Ernest W. Kent

Journal:

Behavioral and Neural Biology

Year:

1980

Language:

english

File:

PDF, 1.08 MB

english, 1980

33

Substituted Hexahydrobenzo[ f ]thieno[ c ]quinolines as Dopamine D1-Selective Agonists: Synthesis and Biological Evaluation in Vitro and in Vivo

Michaelides, Michael R., Hong, Yufeng, DiDomenico, Stanley, Bayburt, Erol K., Asin, Karen E., Britton, Donald R., Lin, Chun Wel, Shiosaki, Kazumi

Journal:

Journal of Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 464 KB

english, 1997

34

(1R,3S)-1-(Aminomethyl)-3,4-dihydro-5,6-dihydroxy-3-phenyl-1H-2-benzopyran: a potent and selective D1 agonist

DeNinno, Michael P., Schoenleber, Robert, Asin, Karen E., MacKenzie, Robert, Kebabian, John W.

Journal:

Journal of Medicinal Chemistry

Year:

1990

Language:

english

File:

PDF, 414 KB

english, 1990

35

Interactive effects of stimulation of D1 and D2 dopamine receptors on fos-like immunoreactivity in the normosensitive rat striatum

Wirtshafter, David, Asin, Karen E.

Journal:

Brain Research Bulletin

Year:

1994

Language:

english

File:

PDF, 1.54 MB

english, 1994

36

A68930: A potent agonist specific for the dopamine D1 receptor

Kebabian, John W., DeNinno, Michael P., Schoenleber, Robert, MacKenzie, Robert, Britton, Donald R., Asin, Karen E.

Journal:

Neurochemistry International

Year:

1992

Language:

english

File:

PDF, 301 KB

english, 1992

37

Evidence that serotonergic projections to the substantia nigra in the rat arise in the dorsal, but not the median, raphe nucleus

Wirtshafter, David, Stratford, Thomas R., Asin, Karen E.

Journal:

Neuroscience Letters

Year:

1987

Language:

english

File:

PDF, 330 KB

english, 1987

38

New applications of disease genetics and pharmacogenetics to drug development

Roses, Allen D, Saunders, Ann M, Lutz, Michael W, Zhang, Nanyin, Hariri, Ahmad R, Asin, Karen E, Crenshaw, Donna G, Budur, Kumar, Burns, Daniel K, Brannan, Stephen K

Journal:

Current Opinion in Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.29 MB

english, 2014

39

Changes in fMRI resting state functional connectivity in rats after acute and repeat dosing with Pioglitazone

Asin, Karen, Crenshaw, Donna, Gottschalk, Kirby, Zhang, Nanyin, Liang, Zifeng, Roses, Allen

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 133 KB

english, 2012

40

Delaying early phases of cognitive decline associated with Alzheimer's disease: Challenges for international phase III therapeutic trials

Brannan, Stephen, Burns, Daniel, Malholtra, Manoj, Talbott, Sheila, Hariri, Ahmad, Asin, Karen, Ogrinc, Francis, Roses, Allen D

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 75 KB

english, 2013

41

Vortioxetine, a novel antidepressant with multimodal activity: Review of preclinical and clinical data

Sanchez, Connie, Asin, Karen E., Artigas, Francesc

Journal:

Pharmacology & Therapeutics

Year:

2015

Language:

english

File:

PDF, 717 KB

english, 2015

42

Synthesis and biological activity of CCK heptapeptide analogs. Effects of conformational constraints and standard modifications on receptor subtype selectivity, functional activity in vitro, and appetite suppression in vivo

Holladay, Mark W., Bennett, Michael J., Tufano, Michael D., Lin, C. W., Asin, Karen E., Witte, David G., Miller, Thomas R., Bianchi, Bruce R., Nikkel, A. L.

Journal:

Journal of Medicinal Chemistry

Year:

1992

Language:

english

File:

PDF, 1.47 MB

english, 1992

43

(5aR,11bS)-4,5,5a,6,7,11b-Hexahydro-2-propyl-3-thia-5-azacyclopent-1-ena[c]phenanthrene-9,10-diol (A-86929): a potent and selective dopamine D1 agonist that maintain behavioral efficacy following repeated administration and characterization of its diacetyl prodrug (ABT-431)

Michaelides, Michael R., Hong, Yufeng, DiDomenico, Stanley, Asin, Karen E., Britton, Donald R., Lin, Chun Wel, Williams, Michael, Shiosaki, Kazumi

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 387 KB

english, 1995

44

Synthesis and dopaminergic activity of 3-substituted 1-(aminomethyl)-3,4-dihydro-5,6-dihydroxy-1H-2-benzopyrans: characterization of an auxiliary binding region in the D1 receptor

DeNinno, Michael P., Schoenleber, Robert, Perner, Richard J., Lijewski, Linda, Asin, Karen E., Britton, Donald R., MacKenzie, Robert, Kebabian, John W.

Journal:

Journal of Medicinal Chemistry

Year:

1991

Language:

english

File:

PDF, 1.13 MB

english, 1991

45

Shock-induced suppression of drinking following electrolytic median raphe lesions

David Wirtshafter,Karen E. Asin

Journal:

Year:

1981

Language:

english

File:

PDF, 1.30 MB

english, 1981

46

Serotonin depletion and inhibition: Running the rat race without any brakes?

Wirtshafter, David, Asin, Karen E.

Journal:

Behavioral and Brain Sciences

Year:

1986

Language:

english

File:

PDF, 5.94 MB

english, 1986

47

Effects of haloperidol and clozapine on Fos expression in the primate striatum

Wirtshafter, David, Asin, Karen E.

Journal:

Year:

2003

Language:

english

File:

PDF, 97 KB

english, 2003

48

Translational Development Strategies for TAK-063, a Phosphodiesterase 10A Inhibitor

Macek, Thomas A, Suzuki, Kazunori, Asin, Karen, Kimura, Haruhide

Journal:

The International Journal of Neuropsychopharmacology

Year:

2020

File:

PDF, 583 KB

2020

49

The application of electrophysiological methods to characterize AMPA receptors in dissociated adult rat and non-human primate cerebellar neurons for use in neuronal safety pharmacology assessments of the central nervous system

Miraucourt, LoÃ¯s S., Accardi, Michael V., Asin, Karen E., Pugsley, Michael K., Curtis, Michael J., Authier, Simon

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2020

File:

PDF, 2.18 MB

2020